butabarbital decreases results of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of CYP3A4 inducers may perhaps lessen sufentanil stages and efficacy, quite possibly precipitating withdrawal syndrome in sufferers who've developed Bodily dependence to sufentanil. Discontinuat