butabarbital decreases results of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of CYP3A4 inducers may perhaps lessen sufentanil stages and efficacy, quite possibly precipitating withdrawal syndrome in sufferers who've developed Bodily dependence to sufentanil. Discontinuation of concomitantly used CYP3A4 inducers could boost sufentanil plasma focus.
Butabarbital, most often called Butisol commercially, can be an accepted Agenda III drug inside the US and Canada Utilized in the short-time period treatment of anxiousness disorders and as being a pre-surgical sedative aid. Authorised professional types are available in pill or elixir sorts.
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butabarbital will lower the level or result of ramelteon by impacting hepatic enzyme CYP2C9/10 metabolism. Insignificant/Importance Not known.
These agents must only be blended if choice procedure options are insufficient. If put together, Restrict the dosages and length of every drug. Think about therapy modification
butabarbital will minimize the extent or result of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
butabarbital will lower the extent or effect of estrogens conjugated artificial by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
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butabarbital will reduce the level or impact of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
butabarbital will minimize the level or outcome of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
butabarbital will here minimize the level or influence of montelukast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unidentified.
butabarbital will lessen the level or outcome of amiodarone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
butabarbital decreases amounts of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral kind of the two brokers. Minimal/Significance Unknown.
butabarbital will increase effects of ifosfamide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. CYP3A4 inducers could increase the metabolism of ifosfamide to its Energetic alkylating metabolites.